Paulo R R Costa Selected Research

Pterocarpans

1/2021	New 5-carba-pterocarpans: Synthesis and preliminary antiproliferative activity on a panel of human cancer cells.
2/2009	(+/-)-3,4-Dihydroxy-8,9-methylenedioxypterocarpan and derivatives: cytotoxic effect on human leukemia cell lines.

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Paulo R R Costa Research Topics

Disease

10	Leukemia 10/2021 - 02/2009
10	Neoplasms (Cancer) 01/2021 - 09/2007
4	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2019 - 12/2011
2	Myotoxicity 01/2019 - 08/2002
2	Snake Bites (Snake Bite) 01/2019 - 01/2004
2	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 06/2014
2	Melanoma (Melanoma, Malignant) 01/2019 - 11/2011
2	Breast Neoplasms (Breast Cancer) 10/2018 - 08/2002
2	Leishmaniasis 01/2018 - 01/2014
2	Visceral Leishmaniasis (Kala Azar) 01/2018 - 05/2017
2	Infections 01/2014 - 08/2002
2	Ischemia 06/2009 - 05/2007
1	Chromosome Aberrations (Chromosome Abnormalities) 01/2021
1	Disease Progression 01/2020
1	Carcinoma (Carcinomatosis) 01/2019
1	Edema (Dropsy) 01/2019
1	Hemorrhage 01/2019
1	Wounds and Injuries (Trauma) 01/2019
1	Cutaneous Leishmaniasis 01/2018
1	Pneumonia (Pneumonitis) 01/2016
1	Myeloproliferative Disorders (Myeloproliferative Disorder) 01/2015
1	Malaria 01/2014
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 02/2013
1	Necrosis 01/2013
1	Colonic Neoplasms (Colon Cancer) 11/2011
1	Cardiotoxicity 02/2010
1	Heart Failure 09/2007
1	Communicable Diseases (Infectious Diseases) 09/2007

Drug/Important Bio-Agent (IBA)

9	LQB 118IBA 01/2019 - 12/2011
7	Pharmaceutical PreparationsIBA 10/2021 - 12/2011
3	Antineoplastic Agents (Antineoplastics)IBA 01/2019 - 05/2015
2	PterocarpansIBA 01/2021 - 02/2009
2	Biological ProductsIBA 01/2019 - 08/2002
2	Imatinib Mesylate (Gleevec)FDA Link 01/2015 - 12/2011
2	lapacholIBA 06/2014 - 12/2011
2	nitronesIBA 06/2009 - 05/2007
1	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2021
1	Collagenases (Collagenase)FDA Link 01/2019
1	Antivenins (Antivenoms)IBA 01/2019
1	Crotalid Venoms (Rattlesnake Venom)IBA 01/2019
1	Snake Venoms (Snake Venom)IBA 01/2019
1	VenomsIBA 01/2019
1	Phospholipases A2 (Phospholipase A2)IBA 01/2019
1	Sirolimus (Rapamycin)FDA Link 10/2016
1	LipopolysaccharidesIBA 01/2016
1	LQB-278IBA 05/2015
1	Oncogene Proteins (Oncogene Protein)IBA 01/2015
1	Tyrosine Kinase InhibitorsIBA 01/2015
1	Messenger RNA (mRNA)IBA 06/2014
1	CyclinsIBA 06/2014
1	Annexin A5IBA 06/2014
1	11a-N-tosyl-5-deoxi-pterocarpanIBA 05/2014
1	Type I DNA Topoisomerases (Topoisomerase I)IBA 01/2014
1	trioctyl phosphine oxide (TOPO)IBA 01/2014
1	Inhibitor of Apoptosis ProteinsIBA 02/2013
1	Propidium (Propidium Iodide)IBA 01/2013
1	CalciumIBA 01/2013
1	Fluo-3IBA 01/2013
1	Caspase 9IBA 01/2013
1	Caspase 12IBA 01/2013
1	3,3'-dihexyl-2,2'-oxacarbocyanineIBA 01/2013
1	AnnexinsIBA 01/2013
1	NaphthoquinonesIBA 12/2011
1	PalladiumIBA 11/2011
1	Alkenes (Olefins)IBA 11/2011
1	PhytohemagglutininsIBA 04/2010
1	wedelolactoneIBA 02/2010
1	AldehydesIBA 06/2009
1	catechol (pyrocatechol)IBA 02/2009
1	quinone (benzoquinone)IBA 02/2009
1	piperonalIBA 05/2007
1	vanillinIBA 05/2007
1	phenyl-N-tert-butylnitroneIBA 05/2007
1	Furaldehyde (Furfural)IBA 05/2007
1	alpha-Tocopherol FDA Link 05/2007
1	edunolIBA 01/2004
1	PoisonsIBA 08/2002

Therapy/Procedure

3	Therapeutics 01/2021 - 09/2007
3	Drug Therapy (Chemotherapy) 01/2020 - 01/2014
1	Surgical Amputation (Amputations) 01/2019
1	Intravenous Administration 06/2009